Anti-AIF Rabbit mAb - Mitochondrial Marker
Catalog number :AT0557
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
- Overview
- Description
- Rabbit monoclonal antibody to AIF
- Reactivity
- Human; Mouse; Monkey; Rat
- Tested applications
- ELISA,
WB:1/500 - 1/2000
- Properties
- Immunogen
- Purified recombinant fragment of human AIF expressed in E. Coli.
- Clonality
- Monoclonal, clone number: 5F2
- Isotype
- Rabbit IgG
- Form
- Ascitic fluid containing 0.03% sodium azide.
- Storage instruction
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C
- Applications
- Application Image
Figure 1: Western blot analysis using AIF antibody against NIH/3T3 (1), Jurkat (2), Hela (3), HepG2 (4), MOLT4 (5), C6 (6), RAJI (7), Cos7 (8) and PC-12 (9) cell lysate.
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