CoIP, ChIP, CUT&RUN, CUT&Tag Expert! My Basket (...)
Worldwide delivery!
Having the Best Alpaca Nanobody Products!
Home | About us | Contact us | How to order |
    My Base Info
    Shopping Basket
    My Orders
    My Shipping Info
    Modify Password
    Log Out

    Anti-FOXP4 antibody - ChIP, CUT&RUN and CUT&Tag Grade

    Catalog number :ATC3001
    loading...
    FoxP4 (Forkhead box protein P4; also FKHLA) is a 70-80 kDa member of the winged helix transcription factor gene family, FoxP subfamily of proteins. It is a transcriptional repressor that is strongly expressed in embryonic gut and lung epithelium, and in neurons both pre-and postnatally. Postnatally, it is found in cerebellar Purkinje cells. During development, it is found in hippocampal hilus, proliferating cells of the ventricular zone, and neurons of the basolateral nucleus of the amygdala. Human FoxP4 is 680 amino acids (aa) in length. It contains a large poly-Gln region (aa 65-219), a C2H2 Zn-finger domain (aa 307-332), a Leu-zipper dimerization motift (aa 349-370) and a forkhead DNA binding domain (aa 467-559). Phosphorylation occurs at Ser360. FoxP4 forms homodimers, and heterodimers with FoxP1 and FoxP2; it does not bind CTBP1. One potential splice form shows a deletion of aa 384-395. Over aa 549-680, human and mouse FoxP4 share 89% aa identity.
    Overview
    Description
    Anti-FOXP4 rabbit monoclonal antibody - ChIP, CUT&RUN and CUT&Tag Grade
    Reactivity
    human,mouse,rat
    Tested applications
    WB: 1:1000
    IHC: 1:200
    ICC/IF:1:200
    COIP: 1:50

    ChIP: 10-20ul per reaction
    CUT&RUN: 2-10ul per reaction
    CUT&Tag: 2-10ul per reaction
    Specificity
    Recognize FOXP4 specifically, do not recognize FOXP1, FOXP2 and FOXP3.
    Properties
    Immunogen
    Synthetic peptide of human FOXP4
    Clonality
    Monoclonal, clone number: 4D8
    Isotype
    rabbit IgG
    Form
    Liquid, 100 μl,1mg/ml, PBS (pH 7.2) and 40% Glycerol,0.02% Sodium Azide
    Storage instruction
    Store at -20°C, Avoid freeze / thaw cycle.
    Database links
    Q8IVH2
    Host
    rabbit
    Applications
    WB Image
    FOXP4 antibody


    Western blot shows lysates of COS-7 African green monkey SV40 transformed kidney fibroblast-like cell line either mock transfected, transfected with human FoxP1, transfected with human FoxP2, transfected with human FoxP3, or transfected with human FoxP4. PVDF membrane was probed with 1:1000 dilution of Anti-FoxP4 Antibody (Catalog # ATC3001) followed by HRP-conjugated Anti-rabbit IgG Secondary Antibody.
    ICC/IF Image
    FOXP4 antibody

    Immunocytochemistry/Immunofluorescence: FoxP4 Antibody - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.

    Related Products

    Reviews

    loading...
    Content *:
    Customer Review :
    Verification Code * :
    refresh image

    Shipping and Paying Info
    ......
    Order Information
    You can place an order online step by step as blow.

    Step 1. Register for a new account and Log in, Find out your product by searching our website.
    Step 2. Add the Product into your shopping basket, select your settlement currency.
    Step 3. Checkout by Paypal, Pay by credit card or bank transfer for your order.
    Step 4. Ship the goods for you, providing you package tracking numbers. 

    Any questions, please contact us via email: sale@engibodybio.com
    Payments by
    All our products are For Research Use Only. Not for diagnostic or therapeutic usages.