Anti-PAX6 Rabbit mAb

Product

Anti-PAX6 Rabbit mAb

Catalog number :AT6610

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Overview

Reactivity: Human Mouse Rat

Tested applications: WB 1:500~1:1000
IHC 1:50~1:200
ICC/IF 1:50~1:200

Specificity: This antibody recognizes endogenous levels of PAX6 protein.

Properties

Immunogen: A synthesized peptide derived from human PAX6

Clonality: Rabbit Monoclonal, clone number: 7S2

Isotype: Rabbit IgG

Form: Liquid, 50 μl,1mg/ml, PBS (pH 7.2) and 50% Glycerol,0.02% Sodium Azide

Storage instruction: Store at -20°C, Avoid freeze / thaw cycle.

Database links: UniProt : P26367

Host: Rabbit

Applications

WB Image: Western blot – Anti-PAX6 Rabbit mAb (AT6610) at 1/1000 dilution

Sample: in Human and mouse brain lysate

Observed band size: 47 kDa

Recommended secondary antibody: Goat anti rabbit IgG-HRP (Engibody, Catalog number:AT0097)

Recommended ECL: ECL Pico-Detect™ Western Chemiluminescent HRP Substrate (Engibody, Catalog number: IF6747)

ICC/IF Image: Immunocytochemistry/Immunofluorescence: Anti-PAX6 Rabbit mAb - Staining of human cell line HEK 293 shows localization to nucleoplasm. Antibody staining is shown in green.

Anti-PAX6 Rabbit mAb

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