anti CD137 Rabbit mAb
Catalog number :AT0556
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
- Overview
- Description
- TNFRSF9 (Homo sapiens tumor necrosis factor receptor superfamily, member 9) rabbit monoclonal antibody, CD137 rabbit monoclonal antibody
- Reactivity
- Human, Mouse, Rat
- Tested applications
- WB 1:500-1:2000
- Properties
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 24-186 of human TNFRSF9 (NP_001552) produced in E.coli.
- Clonality
- Monoclonal, clone number: 5F2
- Isotype
- Rabbit IgG
- Form
- Liquid, PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
- Storage instruction
- Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Applications
- WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF9 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD137 Antibody.
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