Anti-Catalase Rabbit mAb - Peroxisome Marker

Product

Anti-Catalase Rabbit mAb - Peroxisome Marker

Catalog number :AT0809

Background:

Catalase catalyzes the conversion of hydrogen peroxide to water and oxygen. Research studies show that overexpression of this antioxidant enzyme increases the ability of pancreatic β-cells to scavenge reactive oxygen species (ROS), thereby protecting pancreatic β-cells from oxidative stress. The pancreatic β-cells overexpressing this enzyme are also protected from hydrogen peroxide-mediated lipotoxicity, providing further evidence for the importance of catalase in the pathogenesis of diabetes.

Overview

Reactivity: Mouse, Rat, Human, Monkey, Pig, Zebrafish

Tested applications: Western Blotting: 1/1000-1/5000

Immunofluorescence: 1/500

Immunohistochemistry (Paraffin): 1/500

Immunoprecipitation(IP) : 1/100

Optimal dilutions/concentrations should be determined by the end user.

Specificity: This antibody recognizes endogenous levels of total Catalase protein.

Properties

Immunogen: a synthetic peptide corresponding to residues near the carboxy terminus of human catalase protein.

Clonality: Monoclonal, clone number: 5DF7

Isotype: Rabbit IgG

Form: Liquid, 100 μl,1mg/ml, PBS (pH 7.2) and 40% Glycerol，0.02% Sodium Azide

Storage instruction: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C, Avoid freeze / thaw cycle.

Host: Rabbit

Applications

WB Image: Western Blot: Catalase Antibody - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue

IHC Image: Immunohistochemistry-Paraffin: Catalase Antibody - Staining of human pancreas shows low expression as expected.

ICC/IF Image: Immunocytochemistry/Immunofluorescence: Catalase Antibody - Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.

Anti-Catalase Rabbit mAb - Peroxisome Marker

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