Anti-DHFR Rabbit mAb
Catalog number :AT0482
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
- Overview
- Reactivity
- Mouse, Rat, Human
- Tested applications
- Western Blot: 1:1000Immunohistochemistry: 1:500Immunoprecipitation: 1:100
- Specificity
- Recognizes endogenous levels of total DHFR protein.
- Properties
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human DHFR. The exact sequence is proprietary.
- Clonality
- Monoclonal, clone number: 7A7
- Isotype
- Rabbit IgG
- Storage instruction
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C
- Applications
- WB Image
Western Blot: Dihydrofolate reductase Antibody - Sample (30 ug of whole cell lysate) A: 293T B: A431 12% SDS PAGE gel, diluted at 1:1000.
- IHC Image
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution.
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