Anti-STAT6 Rabbit mAb - ChIP, CUT&RUN and CUT&Tag Grade

Product

Anti-STAT6 Rabbit mAb - ChIP, CUT&RUN and CUT&Tag Grade

Catalog number :AT0606

Upon activation by Janus kinases, Stat6 translocates to the nucleus where it regulates cytokine-induced gene expression. Stat6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13. In addition, Stat6 is activated by IFN-α in B cells, where it forms transcriptionally active complexes with Stat2 and p48. Protein phosphatase 2A is also involved in regulation of IL-4-mediated Stat6 signaling.

Overview

Reactivity: Mouse, Rat, Human

Tested applications: Western Blot: 1:1000

Immunohistochemistry: 1:500

Immunoprecipitation: 1:100
ChIP, CUT&RUN and CUT&Tag

Specificity: Recognizes endogenous levels of total Stat6 protein.

Properties

Immunogen: Recombinant protein encompassing a sequence within the center region of human STAT6. The exact sequence is proprietary. Swiss-Prot Acc: P42226

Clonality: Monoclonal, clone number: 4R2

Isotype: Rabbit IgG

Storage instruction: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C

Applications

WB Image: Western Blot: STAT6 Antibody - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000

IHC Image: Immunohistochemistry-Paraffin: STAT6 Antibody - Paraffin-embedded mouse kidney.

STAT6 antibody diluted at 1:500.

Anti-STAT6 Rabbit mAb - ChIP, CUT&RUN and CUT&Tag Grade

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