Anti-Bax Rabbit mAb
Catalog number :AT0550
Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
- Overview
- Description
- anti-Bax Rabbit monoclonal antibody
- Reactivity
- Human, Mouse, Rat
- Tested applications
- WB
- Properties
- Immunogen
- Synthetic peptide corresponding to Human Bax aa 3-16 (Cysteine residue).Sequence: C-GSGEQPRGGGPTSS
- Clonality
- Monoclonal, clone number: 4T2
- Isotype
- Rabbit IgG
- Form
- Liquid
Phosphate buffered saline (PBS) , approx. pH 7.2.
0.05% Sodium Azide
- Storage instruction
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
- Applications
- WB Image
Molecular Weight: 21 kDa
Related Products
| Catalog number | AT0377 |
Reviews
loading...
Payments by 
All our products are For Research Use Only. Not for diagnostic or therapeutic usages.