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    Smart-DRIP™ DRIP Kit

    Catalog number :DRIP-1001
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    The R-loop is a special chromatin structure composed of a heterozygous RNA-DNA strand and a single stranded DNA segment.
     
    R-loops are widely present in the genomes of bacteria, fungi, plants, and animals, accounting for approximately 5% of the mammalian genome, with most concentrated in the transcription initiation and termination regions. It plays an important role in gene transcription, DNA replication, DNA damage repair, and epigenetic modification (histone modification), and is closely related to the occurrence and development of many major diseases, making it a new research hotspot in genome biology in recent years.
     
    Common R loops include mRNA transcription region R loop, Lnc RNA R loop, and Nami RNA enhancer R loop.
    Overview
    Description
    DNA-RNA hybrid Immunoprecipitation (DRIP) kit
    Product Picture
    DNA-RNA hybrid Immunoprecipitation (DRIP)
    Properties
    Components
    Smart-DRIP™ DRIP Kit
    DNA-RNA hybrid Immunoprecipitation (DRIP)

    Item Name Size   Attention
    Store at  4 °C
    DRIP-001 DRIP Grade Protein A/G Magnetic Beads
    (Single strand salmon sperm DNA pre-coated)
    1 mL +4 °C Do not freeze
    DRIP-002 DRIP 10x Binding buffer 0.7 mL +4 °C  
    DRIP-003 DRIP Wash Buffer 1 12 mL +4 °C  
    DRIP-004 DRIP Wash Buffer 2 12 mL +4 °C  
    DRIP-005 DRIP Wash Buffer 3 12 mL +4 °C  
    DRIP-006 DRIP Elution Buffer 3 mL +4 °C  
    GIFT Extraction Reagent D 15 mL +4 °C  
    Store at -20 °C
    DRIP-008 Enzyme L 100 µL -20 °C  
    DRIP-009 RNase Inhibitor 50 µL -20 °C  
    DRIP-010 DNA Precipitation Enhancer 100 µL -20 °C  
    DRIP-011 DRIP Precipitation Buffer 1.5 mL -20 °C  
    DRIP-012 DRIP Grade Normal Mouse IgG 100 µL -20 °C  
    DRIP-013 2×Hot-Start qPCR Master Mix 1.25 mL*2 -20 °C
     
     
     
     

    Structure Figure 1
    DRIP
    Applications
    Application Image
    DNA-RNA hybrid Immunoprecipitation (DRIP)
    Highlights
    1. This kit is suitable for sample types containing R rings, such as bacteria, fungi, insects, adherent cells, suspended cells, animal tissues, and plant tissues.
     
    2. This kit is based on immunoprecipitation of S9.6 antibody and has high resolution, sensitivity, and specificity.
     
    3. This kit is suitable for two downstream experiments of DRIP (qPCR and NGS second-generation sequencing).
    Work Flow Image
    DNA-RNA hybrid Immunoprecipitation (DRIP)
    Application Figure 1
    DRIP KIT
    Application Figure 2
    DRIP
    Application Figure 3
    DRIP
    Application Figure 4
    DRIP

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    All our products are For Research Use Only. Not for diagnostic or therapeutic usages.